Quantitative mass spectrometry of human reticulocytes reveal proteome-wide modifications during maturation

• Main Authors: Chu, Trang T. T., Sinha, Ameya, Malleret, Benoit, Suwanarusk, Rossarin, Park, Jung Eun, Naidu, Renugah, Das, Rupambika, Dutta, Bamaprasad, Ong, Seow Theng, Verma, Navin Kumar, Chan, Jerry K., Nosten, François, Rénia, Laurent, Sze, Siu Kwan, Russell, Bruce, Chandramohanadas, Rajesh
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Red Blood Cells; Reticulocytes
• 在線閱讀: https://hdl.handle.net/10356/87031; http://hdl.handle.net/10220/44297

Erythropoiesis is marked by progressive changes in morphological, biochemical and mechanical properties of erythroid precursors to generate red blood cells (RBC). The earliest enucleated forms derived in this process, known as reticulocytes, are multi-lobular and spherical. As reticulocytes mature,...