Programming Cell Death in the 1960s: Developmental Biology beyond Dichotomy

Programmed cell death (PCD) has been one of the most significant topics in modern biomedical research. Its broad importance in many biological and pathological phenomena, including morphogenesis, autoimmune disease, and cancer, demonstrates that its origin deserves a historical examination. By analy...

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Bibliographic Details
Main Author: Park, Hyung Wook
Other Authors: School of Humanities and Social Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87070
http://hdl.handle.net/10220/44272
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Institution: Nanyang Technological University
Language: English
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Summary:Programmed cell death (PCD) has been one of the most significant topics in modern biomedical research. Its broad importance in many biological and pathological phenomena, including morphogenesis, autoimmune disease, and cancer, demonstrates that its origin deserves a historical examination. By analyzing the role of developmental biology of the 1960s in shaping the notion of a program, this paper explains the emergence of a close correlation between not only life and death, but also the normal and the pathological in the postwar study of cell death.