Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems

Significant progress on upconversion-nanoparticle (UCNP)-based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non-autofluorescence, high chemical stability, large l...

Full description

Saved in:
Bibliographic Details
Main Authors: Gu, Bin, Zhang, Qichun
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87265
http://hdl.handle.net/10220/44379
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:Significant progress on upconversion-nanoparticle (UCNP)-based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non-autofluorescence, high chemical stability, large light-penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide-doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP-based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide.