Our Gut Microbiome: The Evolving Inner Self

Our Gut Microbiome: The Evolving Inner Self

The “holobiont” concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive view of human evolution and personalized characteristics. Here, we provide snaps...

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Main Authors: Kundu, Parag, Blacher, Eran, Elinav, Eran, Pettersson, Sven
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Microbiome
Aging
Online Access:https://hdl.handle.net/10356/87346
http://hdl.handle.net/10220/44421
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-873462020-09-21T11:34:34Z Our Gut Microbiome: The Evolving Inner Self Kundu, Parag Blacher, Eran Elinav, Eran Pettersson, Sven Lee Kong Chian School of Medicine (LKCMedicine) Singapore Centre for Environmental Life Sciences Engineering Microbiome Aging The “holobiont” concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive view of human evolution and personalized characteristics. Here, we provide snapshots of the evolving microbial-host associations and relations during distinct milestones across the lifespan of a human being. We discuss the current knowledge of biological symbiosis between the microbiome and its host and portray the challenges in understanding these interactions and their potential effects on human physiology, including microbiome-nervous system inter-relationship and its relevance to human variation and individuality. MOE (Min. of Education, S’pore) Accepted version 2018-02-09T02:28:15Z 2019-12-06T16:40:00Z 2018-02-09T02:28:15Z 2019-12-06T16:40:00Z 2017 Journal Article Kundu, P., Blacher, E., Elinav, E., & Pettersson, S. (2017). Our Gut Microbiome: The Evolving Inner Self. Cell, 171(7), 1481-1493. 0092-8674 https://hdl.handle.net/10356/87346 http://hdl.handle.net/10220/44421 10.1016/j.cell.2017.11.024 en Cell © 2017 Elsevier Inc. This is the author created version of a work that has been peer reviewed and accepted for publication by Cell, Elsevier Inc. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.cell.2017.11.024]. 34 p. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic Microbiome
Aging
spellingShingle Microbiome
Aging
Kundu, Parag
Blacher, Eran
Elinav, Eran
Pettersson, Sven
Our Gut Microbiome: The Evolving Inner Self
description The “holobiont” concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive view of human evolution and personalized characteristics. Here, we provide snapshots of the evolving microbial-host associations and relations during distinct milestones across the lifespan of a human being. We discuss the current knowledge of biological symbiosis between the microbiome and its host and portray the challenges in understanding these interactions and their potential effects on human physiology, including microbiome-nervous system inter-relationship and its relevance to human variation and individuality.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Kundu, Parag
Blacher, Eran
Elinav, Eran
Pettersson, Sven
format Article
author Kundu, Parag
Blacher, Eran
Elinav, Eran
Pettersson, Sven
author_sort Kundu, Parag
title Our Gut Microbiome: The Evolving Inner Self
title_short Our Gut Microbiome: The Evolving Inner Self
title_full Our Gut Microbiome: The Evolving Inner Self
title_fullStr Our Gut Microbiome: The Evolving Inner Self
title_full_unstemmed Our Gut Microbiome: The Evolving Inner Self
title_sort our gut microbiome: the evolving inner self
publishDate 2018
url https://hdl.handle.net/10356/87346
http://hdl.handle.net/10220/44421
_version_ 1681058322935971840

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