The Viability of Single Cancer Cells after Exposure to Hydrodynamic Shear Stresses in a Spiral Microchannel: A Canine Cutaneous Mast Cell Tumor Model

• Main Authors: Ketpun, Dettachai, Sailasuta, Achariya, Suwannaphan, Thammawit, Bhanpattanakul, Sudchaya, Pimpin, Alongkorn, Srituravanich, Werayut, Sripumkhai, Witsaroot, Jeamsaksiri, Wutthinan, Piyaviriyakul, Prapruddee
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Hydrodynamic Shear Stress; Microfluidic
• Online Access: https://hdl.handle.net/10356/87404; http://hdl.handle.net/10220/44404
• Institution: Nanyang Technological University

Our laboratory has the fundamental responsibility to study cancer stem cells (CSC) in various models of human and animal neoplasms. However, the major impediments that spike our accomplishment are the lack of universal biomarkers and cellular heterogeneity. To cope with these restrictions, we have t...