The public health value of vaccines beyond efficacy: methods, measures and outcomes

• Main Authors: Wilder-Smith, Annelies, Longini, I., Zuber, P. L., Bärnighausen, T., Edmunds, W. J., Dean, N., Spicher, V. Masserey, Benissa, M. R., Gessner, B. D.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Vaccine Efficacy; Effectiveness
• Online Access: https://hdl.handle.net/10356/87436; http://hdl.handle.net/10220/45359
• Institution: Nanyang Technological University

Background: Assessments of vaccine efficacy and safety capture only the minimum information needed for regulatory approval, rather than the full public health value of vaccines. Vaccine efficacy provides a measure of proportionate disease reduction, is usually limited to etiologically confirmed dise...