A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure

• Main Authors: Korolev, Nikolay, Lyubartsev, Alexander P., Nordenskiöld, Lars
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Nucleosome Core Particles (NCPs); Stacked Nucleosomes
• Online Access: https://hdl.handle.net/10356/87537; http://hdl.handle.net/10220/45421
• Institution: Nanyang Technological University

Chromatin condensation is driven by the energetically favourable interaction between nucleosome core particles (NCPs). The close NCP-NCP contact, stacking, is a primary structural element of all condensed states of chromatin in vitro and in vivo. However, the molecular structure of stacked nucleosom...