Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow

Microfluidic manipulation of particulate matters has found its applications in cell handling, virus detection, biomolecule concentration and colloidal particle assembly etc. In the literature, optical tweezing, electrophoresis, and dielectrophoresis are well-established techniques for particle manip...

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Main Authors: Zhao, C., Yang, C.
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2018
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Online Access:https://hdl.handle.net/10356/87595
http://hdl.handle.net/10220/46774
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-875952023-03-04T17:16:22Z Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow Zhao, C. Yang, C. School of Mechanical and Aerospace Engineering AFM2014 DRNTU::Engineering::Mechanical engineering Microfluidics Induced-charge Electrokinetic Flow Microfluidic manipulation of particulate matters has found its applications in cell handling, virus detection, biomolecule concentration and colloidal particle assembly etc. In the literature, optical tweezing, electrophoresis, and dielectrophoresis are well-established techniques for particle manipulations, but these techniques have their respective limitations such as low throughput and high costs for optical tweezing, charged particles required for electrophoresis, complex electrode design for dielectrophoresis. Induced charge electrokinetic (ICEK) flows belong to a new class of flows. One of the basic features for ICEK is the generation of vortices over polarisable surfaces. In literature, these kind of nonlinear vortical flows naturally lend themselves to the mixing enhancement in microfluidic devices. Other than the microfluidic mixing, the applications of induced-charge electrokinetics in microfluidics are very rare. Here a novel and high-throughput technique relying on the induced-charge electrokinetics is proposed and demonstrated for simultaneous trapping and concentration of submicron- to micron-sized particles. The fabricated microfluidic device is simply composed of a straight channel and a gold patch on the bottom wall of channel. Under DC-biased AC electric driving voltages, the trapping of particles over the edge of the conducting gold patch are achieved. Moreover, systematic studies are conducted to investigate the effects AC frequency, AC amplitude, DC offset and particle size on the performance of trapping and concentration by ICEK. In addition, a numerical model is developed to explain the underlying mechanisms of particle trapping via ICEK. Published version 2018-12-03T07:10:03Z 2019-12-06T16:45:16Z 2018-12-03T07:10:03Z 2019-12-06T16:45:16Z 2014 Journal Article Zhao, C., & Yang, C. (2014). Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow. WIT Transactions on Engineering Sciences, 82, 253-264. doi:10.2495/AFM140221 1743-3533 https://hdl.handle.net/10356/87595 http://hdl.handle.net/10220/46774 10.2495/AFM140221 en WIT Transactions on Engineering Sciences © 2014 WIT Press. This paper was published in WIT Transactions on Engineering Sciences and is made available as an electronic reprint (preprint) with permission of WIT Press. The published version is available at: [http://dx.doi.org/10.2495/AFM140221]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 12 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Mechanical engineering
Microfluidics
Induced-charge Electrokinetic Flow
spellingShingle DRNTU::Engineering::Mechanical engineering
Microfluidics
Induced-charge Electrokinetic Flow
Zhao, C.
Yang, C.
Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
description Microfluidic manipulation of particulate matters has found its applications in cell handling, virus detection, biomolecule concentration and colloidal particle assembly etc. In the literature, optical tweezing, electrophoresis, and dielectrophoresis are well-established techniques for particle manipulations, but these techniques have their respective limitations such as low throughput and high costs for optical tweezing, charged particles required for electrophoresis, complex electrode design for dielectrophoresis. Induced charge electrokinetic (ICEK) flows belong to a new class of flows. One of the basic features for ICEK is the generation of vortices over polarisable surfaces. In literature, these kind of nonlinear vortical flows naturally lend themselves to the mixing enhancement in microfluidic devices. Other than the microfluidic mixing, the applications of induced-charge electrokinetics in microfluidics are very rare. Here a novel and high-throughput technique relying on the induced-charge electrokinetics is proposed and demonstrated for simultaneous trapping and concentration of submicron- to micron-sized particles. The fabricated microfluidic device is simply composed of a straight channel and a gold patch on the bottom wall of channel. Under DC-biased AC electric driving voltages, the trapping of particles over the edge of the conducting gold patch are achieved. Moreover, systematic studies are conducted to investigate the effects AC frequency, AC amplitude, DC offset and particle size on the performance of trapping and concentration by ICEK. In addition, a numerical model is developed to explain the underlying mechanisms of particle trapping via ICEK.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Zhao, C.
Yang, C.
format Article
author Zhao, C.
Yang, C.
author_sort Zhao, C.
title Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
title_short Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
title_full Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
title_fullStr Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
title_full_unstemmed Trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
title_sort trapping of submicron and micron-sized particles using innovative induced-charge electrokinetic flow
publishDate 2018
url https://hdl.handle.net/10356/87595
http://hdl.handle.net/10220/46774
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