A short tandem repeat-enriched RNA assembles a nuclear compartment to control alternative splicing and promote cell survival

• Main Authors: Tan, Jason S. C., Yap, Karen, Mukhina, Svetlana, Zhang, Gen, Ong, Hong Sheng, Makeyev, Eugene V.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Long Noncoding RNA; Short Tandem Repeats; Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/87602; http://hdl.handle.net/10220/50329
• Institution: Nanyang Technological University

Functions of many long noncoding RNAs (lncRNAs) depend on their ability to interact with multiple copies of specific RNA-binding proteins (RBPs). Here, we devised a workflow combining bioinformatics and experimental validation steps to systematically identify RNAs capable of multivalent RBP recruitm...