Upregulation of epidermal gap junctional proteins in patients with venous disease

• Main Authors: Kanapathy, Muholan, Simpson, R., Madden, Leigh, Thrasivoulou, C., Mosahebi, A., Becker, David Lawrence, Richards, T.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Pathological Skin; CEAP
• Online Access: https://hdl.handle.net/10356/87682; http://hdl.handle.net/10220/45470
• Institution: Nanyang Technological University

Background Leg ulceration is a feared complication of venous insufficiency. It is not known whether varicose veins predispose skin to poor wound healing. The expression pattern of gap junctional protein connexin, a known marker of poor wound healing, was investigated across various stages of venous...