Peroxisome proliferator activated receptor gamma controls mature brown adipocyte inducibility through glycerol kinase

• Main Authors: Lasar, David, Rosenwald, Matthias, Kiehlmann, Elke, Balaz, Miroslav, Tall, Bettina, Opitz, Lennart, Lidell, Martin E., Zamboni, Nicola, Krznar, Petra, Sun, Wenfei, Varga, Lukas, Stefanicka, Patrik, Ukropec, Jozef, Nuutila, Pirjo, Virtanen, Kirsi, Amri, Ez-Zoubir, Enerbäck, Sven, Wahli, Walter, Wolfrum, Christian
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Brown Adipose Tissue; PPAR Gamma
• Online Access: https://hdl.handle.net/10356/87683; http://hdl.handle.net/10220/45503
• Institution: Nanyang Technological University

Peroxisome proliferator-activated receptors (PPARs) have been suggested as the master regulators of adipose tissue formation. However, their role in regulating brown fat functionality has not been resolved. To address this question, we generated mice with inducible brown fat-specific deletions of PP...