Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes

• Main Authors: Mishra, Rajashree, Chesi, Alessandra, Cousminer, Diana L., Hawa, Mohammad I., Bradfield, Jonathan P., Hodge, Kenyaita M., Guy, Vanessa C., Hakonarson, Hakon, Mauricio, Didac, Schloot, Nanette C., Yderstræde, Knud B., Voight, Benjamin F., Schwartz, Stanley, Boehm, Bernhard Otto, Leslie, Richard David, Grant, Struan F. A.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Latent Autoimmune Diabetes In Adults; Genetic Risk Scores
• Online Access: https://hdl.handle.net/10356/87997; http://hdl.handle.net/10220/44546
• Institution: Nanyang Technological University

Background: In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as ‘latent autoimmune diabetes in adults’ (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci in a large cohort of LADA cases to assess wher...