Novel application of in vivo micro-optical coherence tomography to assess cornea scarring in an animal model

• Main Authors: Ang, Marcus, Devarajan, Kavya, Das, Suchandrima, Yam, Gary H. F., Htoon, Hla Mynt, Chen, Si, Liu, Xinyu, Liu, Linbo, Girard, Michael, Mehta, Jodhbir S.
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Cornea Scarring; DRNTU::Engineering::Electrical and electronic engineering; Micro-Optical Coherence Tomography (micro-OCT)
• 在線閱讀: https://hdl.handle.net/10356/88160; http://hdl.handle.net/10220/45657

This pilot study uses a micro-optical coherence tomography (micro-OCT) system with ~1 μm axial resolution specifically to image the cornea and corneal scars in vivo. We used an established murine corneal scar model by irregular phototherapeutic keratectomy in ten C57BL/6 mice, with serial imaging us...