Centrosome- and Golgi-Localized Protein Kinase N-Associated Protein Serves As a Docking Platform for Protein Kinase A Signaling and Microtubule Nucleation in Migrating T-Cells

• Main Authors: Ong, Seow Theng, Chalasani, Madhavi Latha Somaraju, Turabe Fazil, Mobashar Hussain Urf, Prasannan, Praseetha, Kizhakeyil, Atish, Wright, Graham D., Kelleher, Dermot, Verma, Navin Kumar
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: T-cell Migration; AKAP450
• Online Access: https://hdl.handle.net/10356/88474; http://hdl.handle.net/10220/44628
• Institution: Nanyang Technological University

Centrosome- and Golgi-localized protein kinase N-associated protein (CG-NAP), also known as AKAP450, is a cytosolic scaffolding protein involved in the targeted positioning of multiple signaling molecules, which are critical for cellular functioning. Here, we show that CG-NAP is predominantly expres...