CAV-2 vector development and gene transfer in the central and peripheral nervous systems

• Main Authors: Rio, Danila del, Beucher, Bertrand, Lavigne, Marina, Wehbi, Amani, Dopeso-Reyes, Iria Gonzalez, Saggio, Isabella, Kremer, Eric J.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Adenovirus; CAV-2; Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88500; http://hdl.handle.net/10220/49308
• Institution: Nanyang Technological University

The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to many structures and nuclei. These cassettes c...