Tissue-resident CD169 + macrophages form a crucial front line against plasmodium infection

• المؤلفون الرئيسيون: Gupta, Pravesh, Lai, Si Min, Sheng, Jianpeng, Tetlak, Piotr, Balachander, Akhila, Claser, Carla, Renia, Laurent, Karjalainen, Klaus, Ruedl, Christiane
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Macrophages; Plasmodium Berghei Infection; DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/88661; http://hdl.handle.net/10220/46948
• المؤسسة: Nanyang Technological University

Tissue macrophages exhibit diverse functions, ranging from the maintenance of tissue homeostasis, including clearance of senescent erythrocytes and cell debris, to modulation of inflammation and immunity. Their contribution to the control of blood-stage malaria remains unclear. Here, we show that in...