On-chip generation of microbubbles in photoacoustic contrast agents for dual modal ultrasound/photoacoustic in vivo animal imaging

• Main Authors: Das, Dhiman, Sivasubramanian, Kathyayini, Yang, Chun, Pramanik, Manojit
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Imaging Techniques; Biomedical Engineering
• Online Access: https://hdl.handle.net/10356/88778; http://hdl.handle.net/10220/44719
• Institution: Nanyang Technological University

Dual-modal photoacoustic (PA) and ultrasound (US) contrast agents are becoming increasingly popular in recent years. Here, a flow-focusing junction based microfluidic device is used for the generation of nitrogen microbubbles (<7 μm) in two photoacoustic contrast agents: methylene blue (MB) and b...