Engineering nanoparticle synthesis using microbial factories
Biologically engineered entities have enabled discoveries in the past decade and a half, spanning from novel routes for the syntheses of drugs and value-added products to carbon capture. The precise cellular re-programming has extended to the production of nanomaterials owing to their ever-growing d...
Saved in:
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/88893 http://hdl.handle.net/10220/44784 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
id |
sg-ntu-dr.10356-88893 |
---|---|
record_format |
dspace |
spelling |
sg-ntu-dr.10356-888932023-12-29T06:46:21Z Engineering nanoparticle synthesis using microbial factories Pasula, Rupali Reddy Lim, Sierin School of Chemical and Biomedical Engineering NTU-Northwestern Institute for Nanomedicine Nanoparticle Synthesis Microbial Reaction Vessels Biologically engineered entities have enabled discoveries in the past decade and a half, spanning from novel routes for the syntheses of drugs and value-added products to carbon capture. The precise cellular re-programming has extended to the production of nanomaterials owing to their ever-growing demand. The primary advantage of the biological nanoparticle synthesis is the eco-friendly approach performed at ambient temperature and pressure, where the usage of harsh chemical stabilisers and capping agents is eliminated, providing ease of handling and downstream processing. Although the techniques hold great promise, many short comings hamper their scalability; thus, rendering them unsuitable for industrial applications. A fundamental understanding of the underlying mechanisms which involve various enzymes of different metabolic pathways is most crucial in surmounting these impending blocks leading to successfully engineered systems which can be tuned in accordance with the goals of specific applications. This mini review highlights the recent developments in nanoparticle synthesis that employ the use of microbial reaction vessels with specific emphasis on engineering of these biological entities such as bacteria, yeast, fungi and algae. Also presented are the challenges and future trends in this domain where novel and engineered approaches will be the most consequential. Published version 2018-05-14T09:22:23Z 2019-12-06T17:13:13Z 2018-05-14T09:22:23Z 2019-12-06T17:13:13Z 2017 2017 Journal Article Pasula, R. R., & Lim, S. (2017). Engineering nanoparticle synthesis using microbial factories. Engineering Biology, 1(1), 12-17. https://hdl.handle.net/10356/88893 http://hdl.handle.net/10220/44784 10.1049/enb.2017.0009 207299 en Engineering Biology © 2017 The author(s). This is an open access article published by the IET under the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/3.0/). 6 p. application/pdf |
institution |
Nanyang Technological University |
building |
NTU Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NTU Library |
collection |
DR-NTU |
language |
English |
topic |
Nanoparticle Synthesis Microbial Reaction Vessels |
spellingShingle |
Nanoparticle Synthesis Microbial Reaction Vessels Pasula, Rupali Reddy Lim, Sierin Engineering nanoparticle synthesis using microbial factories |
description |
Biologically engineered entities have enabled discoveries in the past decade and a half, spanning from novel routes for the syntheses of drugs and value-added products to carbon capture. The precise cellular re-programming has extended to the production of nanomaterials owing to their ever-growing demand. The primary advantage of the biological nanoparticle synthesis is the eco-friendly approach performed at ambient temperature and pressure, where the usage of harsh chemical stabilisers and capping agents is eliminated, providing ease of handling and downstream processing. Although the techniques hold great promise, many short comings hamper their scalability; thus, rendering them unsuitable for industrial applications. A fundamental understanding of the underlying mechanisms which involve various enzymes of different metabolic pathways is most crucial in surmounting these impending blocks leading to successfully engineered systems which can be tuned in accordance with the goals of specific applications. This mini review highlights the recent developments in nanoparticle synthesis that employ the use of microbial reaction vessels with specific emphasis on engineering of these biological entities such as bacteria, yeast, fungi and algae. Also presented are the challenges and future trends in this domain where novel and engineered approaches will be the most consequential. |
author2 |
School of Chemical and Biomedical Engineering |
author_facet |
School of Chemical and Biomedical Engineering Pasula, Rupali Reddy Lim, Sierin |
format |
Article |
author |
Pasula, Rupali Reddy Lim, Sierin |
author_sort |
Pasula, Rupali Reddy |
title |
Engineering nanoparticle synthesis using microbial factories |
title_short |
Engineering nanoparticle synthesis using microbial factories |
title_full |
Engineering nanoparticle synthesis using microbial factories |
title_fullStr |
Engineering nanoparticle synthesis using microbial factories |
title_full_unstemmed |
Engineering nanoparticle synthesis using microbial factories |
title_sort |
engineering nanoparticle synthesis using microbial factories |
publishDate |
2018 |
url |
https://hdl.handle.net/10356/88893 http://hdl.handle.net/10220/44784 |
_version_ |
1787136496431529984 |