Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin

• Main Authors: Rajan, Sreekanth, Prakash, Ajit, Shin, Joon, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: FK506-binding domain (FKBD); Nucleic Acid; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88977; http://hdl.handle.net/10220/46041
• Institution: Nanyang Technological University

The nuclear immunophilin FKBP25 interacts with chromatin-related proteins and transcription factors and is suggested to interact with nucleic acids. Currently the structural basis of nucleic acid binding by FKBP25 is unknown. Here we determined the nuclear magnetic resonance (NMR) solution structure...