Bevacizumab promotes T-cell–mediated collagen deposition in the mouse model of conjunctival scarring

• Main Authors: Seet, Li-Fong, Toh, Li Zhen, Chu, Stephanie, Finger, Sharon N., Ginhoux, Florent, Hong, Wanjin, Wong, Tina Tzee Ling
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Collagen; DRNTU::Engineering::Materials; Bevacizumab
• Online Access: https://hdl.handle.net/10356/89078; http://hdl.handle.net/10220/47675
• Institution: Nanyang Technological University

Purpose: We determine the effects of bevacizumab on collagen production in a mouse model of conjunctival scarring. Methods: Experimental surgery was performed as described for the mouse model of conjunctival scarring, and bevacizumab was introduced by conjunctival injection. The capacity of bevacizu...