A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator

• Main Authors: Ghim, Mean, Pang, Kuin T., Arshad, Mehwish, Wang, Xiaomeng, Weinberg, Peter D.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Segmenting Growth; Endothelial Cells; DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/89080; http://hdl.handle.net/10220/46108
• Institution: Nanyang Technological University

Background: Effects of shear stress on endothelium are important for the normal physiology of blood vessels and are implicated in the pathogenesis of atherosclerosis. They have been extensively studied in vitro. In one paradigm, endothelial cells are cultured in devices that produce spatially varyin...