Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics

• Main Authors: Kam, Antony, Dutta, Bamaprasad, Loo, Shining, Tam, James P., Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Biological sciences; Bioenergetics; Peptides
• Online Access: https://hdl.handle.net/10356/89096; http://hdl.handle.net/10220/48850
• Institution: Nanyang Technological University

Mitochondria are attractive therapeutic targets for developing agents to delay age-related frailty and diseases. However, few promising leads have been identified from natural products. Previously, we identified roseltide rT1, a hyperstable 27-residue cysteine-rich peptide from Hibiscus sabdarif...