No association between resistance mutations, empiric antibiotic, and mortality in ceftriaxone-resistant Escherichia coli and Klebsiella pneumoniae bacteremia

• Main Authors: Lye, David Chienboon, Ng, Tat Ming, Heng, Shi Thong, Chen, Swaine L., Wong, Joshua G. X.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Resistance Mutations; DRNTU::Science::Medicine; Mortality
• Online Access: https://hdl.handle.net/10356/89126; http://hdl.handle.net/10220/46117
• Institution: Nanyang Technological University

The objective of this study was to correlate resistance mutations of extended spectrum beta-lactamases (ESBL) and AmpC beta-lactamases and virulence factors (VF) with 30-day mortality in patients treated with either piperacillin-tazobactam or carbapenems. A post-hoc analysis on 123 patients with cef...