No association between resistance mutations, empiric antibiotic, and mortality in ceftriaxone-resistant Escherichia coli and Klebsiella pneumoniae bacteremia

• Main Authors: Lye, David Chienboon, Ng, Tat Ming, Heng, Shi Thong, Chen, Swaine L., Wong, Joshua G. X.
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Resistance Mutations; DRNTU::Science::Medicine; Mortality
• 在線閱讀: https://hdl.handle.net/10356/89126; http://hdl.handle.net/10220/46117
• 機構: Nanyang Technological University

The objective of this study was to correlate resistance mutations of extended spectrum beta-lactamases (ESBL) and AmpC beta-lactamases and virulence factors (VF) with 30-day mortality in patients treated with either piperacillin-tazobactam or carbapenems. A post-hoc analysis on 123 patients with cef...