Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery

• Main Authors: Huang, Bu-Wei, Ping, Yuan, You, Jian, Gao, Jian-Qing, Li, Ying, Wang, Meng
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Liposomes; Doxorubicin
• Online Access: https://hdl.handle.net/10356/89142; http://hdl.handle.net/10220/44818
• Institution: Nanyang Technological University

Although widely used in chemotherapy, free doxorubicin (Dox) might enhance cell malignancy undesirably. Liposomal Dox (Doxlipo) has been clinically approved for the treatment of breast cancer due to reduced systematical toxicity and increased tumor targeting, yet the transcriptome-wide elucidation o...