Structural complexity of filaments formed from the actin and tubulin folds

• Main Authors: Jiang, Shimin, Ghoshdastider, Umesh, Narita, Akihiro, Popp, David, Robinson, Robert Charles
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Actin; Evolution; DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/89146; http://hdl.handle.net/10220/47022
• Institution: Nanyang Technological University

From yeast to man, an evolutionary distance of 1.3 billion years, the F-actin filament structure has been conserved largely in line with the 94% sequence identity. The situation is entirely different in bacteria. In comparison to eukaryotic actins, the bacterial actin-like proteins (ALPs) show mediu...