Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways

Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways

High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging t...

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Bibliographic Details
Main Authors: Leung, Hui Min, Cui, Dongyao, Ford, Timothy N., Hyun, Daryl, Dong, Jing, Yin, Biwei, Birket, Susan E., Solomon, George M., Liu, Linbo, Rowe, Steven M., Tearney, Guillermo J.
Other Authors: Raghavachari, Ramesh
Format: Conference or Workshop Item
Language:English
Published: 2018
Subjects:
Cystic Fibrosis
Imaging Techniques
Online Access:https://hdl.handle.net/10356/89458
http://hdl.handle.net/10220/44956
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Institution: Nanyang Technological University
Language: English
Description
Summary:High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways.

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