Benchmarking selected computational gene network growing tools in context of virus-host interactions

• Main Authors: Taye, Biruhalem, Vaz, Candida, Tanavde, Vivek, Kuznetsov, Vladimir A., Eisenhaber, Frank, Sugrue, Richard J., Maurer-Stroh, Sebastian
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Network Growing Tools; SiRNA Screening Study
• Online Access: https://hdl.handle.net/10356/89469; http://hdl.handle.net/10220/44978
• Institution: Nanyang Technological University

Several available online tools provide network growing functions where an algorithm utilizing different data sources suggests additional genes/proteins that should connect an input gene set into functionally meaningful networks. Using the well-studied system of influenza host interactions, we compar...