Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking

• Main Authors: Chen, Susu, Augustine, George James, Chadderton, Paul
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Neuromodulation; Signal Processing
• Online Access: https://hdl.handle.net/10356/89516; http://hdl.handle.net/10220/44970
• Institution: Nanyang Technological University

Purkinje cells (PCs) in Crus 1 represent whisker movement via linear changes in firing rate, but the circuit mechanisms underlying this coding scheme are unknown. Here we examine the role of upstream inputs to PCs—excitatory granule cells (GCs) and inhibitory molecular layer interneurons—in processi...