Bacteria display differential growth and adhesion characteristics on human hair shafts
Apart from the skin surface, hair represents a significant tissue component with a capacity of bacterial interactions. New information can be obtained about hair function through the characterization of bacterial adherence, colonization, and responses to hair shafts per se. In this proof-of-principl...
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sg-ntu-dr.10356-896832020-11-01T05:10:56Z Bacteria display differential growth and adhesion characteristics on human hair shafts Kerk, Swat Kim Lai, Hui Ying Sze, Siu Kwan Ng, Kee Woei Schmidtchen, Artur Adav, Sunil Shankar School of Materials Science & Engineering School of Biological Sciences Interdisciplinary Graduate School (IGS) Lee Kong Chian School of Medicine (LKCMedicine) Nanyang Environment and Water Research Institute DRNTU::Science::Biological sciences Hair Shaft S. Aureus Apart from the skin surface, hair represents a significant tissue component with a capacity of bacterial interactions. New information can be obtained about hair function through the characterization of bacterial adherence, colonization, and responses to hair shafts per se. In this proof-of-principle study, we examine the growth kinetics of Gram-positive Staphylococcus aureus and Staphylococcus epidermidis, and Gram-negative Pseudomonas aeruginosa and Escherichia coli in the presence of human hair shafts. We explore the ability of these bacteria to adhere to and colonize hair shaft surfaces, as well as the resulting impact on the hair’s surface morphology. We show that hair shafts inhibit the growth of Gram-positive S. aureus and S. epidermidis, while the growth kinetics of P. aeruginosa and E. coli remain unaffected. Scanning electron microscope analysis and steeping studies show that P. aeruginosa and E. coli to adhere to and colonize on human hair shafts without significantly affecting the hair shaft’s surface morphology. P. aeruginosa produced a substantial amount of biofilm on the hair shaft surfaces, while E. coli specifically inhabited the edges of the cuticle scales. Taken together, our results demonstrate differences in bacterial responses to human hair shafts, which may provide novel insights into hair and scalp health. MOE (Min. of Education, S’pore) Published version 2018-10-15T09:14:46Z 2019-12-06T17:31:07Z 2018-10-15T09:14:46Z 2019-12-06T17:31:07Z 2018 Journal Article Kerk, S. K., Lai, H. Y., Sze, S. K., Ng, K. W., Schmidtchen, A., & Adav, S. S. (2018). Bacteria display differential growth and adhesion characteristics on human hair shafts. Frontiers in Microbiology, 9, 2145-. doi:10.3389/fmicb.2018.02145 https://hdl.handle.net/10356/89683 http://hdl.handle.net/10220/46324 10.3389/fmicb.2018.02145 en Frontiers in Microbiology © 2018 Kerk, Lai, Sze, Ng, Schmidtchen and Adav. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. 9 p. application/pdf |
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DRNTU::Science::Biological sciences Hair Shaft S. Aureus Kerk, Swat Kim Lai, Hui Ying Sze, Siu Kwan Ng, Kee Woei Schmidtchen, Artur Adav, Sunil Shankar Bacteria display differential growth and adhesion characteristics on human hair shafts |
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Apart from the skin surface, hair represents a significant tissue component with a capacity of bacterial interactions. New information can be obtained about hair function through the characterization of bacterial adherence, colonization, and responses to hair shafts per se. In this proof-of-principle study, we examine the growth kinetics of Gram-positive Staphylococcus aureus and Staphylococcus epidermidis, and Gram-negative Pseudomonas aeruginosa and Escherichia coli in the presence of human hair shafts. We explore the ability of these bacteria to adhere to and colonize hair shaft surfaces, as well as the resulting impact on the hair’s surface morphology. We show that hair shafts inhibit the growth of Gram-positive S. aureus and S. epidermidis, while the growth kinetics of P. aeruginosa and E. coli remain unaffected. Scanning electron microscope analysis and steeping studies show that P. aeruginosa and E. coli to adhere to and colonize on human hair shafts without significantly affecting the hair shaft’s surface morphology. P. aeruginosa produced a substantial amount of biofilm on the hair shaft surfaces, while E. coli specifically inhabited the edges of the cuticle scales. Taken together, our results demonstrate differences in bacterial responses to human hair shafts, which may provide novel insights into hair and scalp health. |
author2 |
School of Materials Science & Engineering |
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School of Materials Science & Engineering Kerk, Swat Kim Lai, Hui Ying Sze, Siu Kwan Ng, Kee Woei Schmidtchen, Artur Adav, Sunil Shankar |
format |
Article |
author |
Kerk, Swat Kim Lai, Hui Ying Sze, Siu Kwan Ng, Kee Woei Schmidtchen, Artur Adav, Sunil Shankar |
author_sort |
Kerk, Swat Kim |
title |
Bacteria display differential growth and adhesion characteristics on human hair shafts |
title_short |
Bacteria display differential growth and adhesion characteristics on human hair shafts |
title_full |
Bacteria display differential growth and adhesion characteristics on human hair shafts |
title_fullStr |
Bacteria display differential growth and adhesion characteristics on human hair shafts |
title_full_unstemmed |
Bacteria display differential growth and adhesion characteristics on human hair shafts |
title_sort |
bacteria display differential growth and adhesion characteristics on human hair shafts |
publishDate |
2018 |
url |
https://hdl.handle.net/10356/89683 http://hdl.handle.net/10220/46324 |
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1683493033952149504 |