Examining practical feasibility of amorphous curcumin-chitosan nanoparticle complex as solubility enhancement strategy of curcumin : scaled-up production, dry powder transformation, and long-term physical stability

• Main Authors: Wong, Jerome Jie Long, Yu, Hong, Hadinoto, Kunn
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Dissolution; DRNTU::Engineering::Chemical engineering; Nanoparticles
• Online Access: https://hdl.handle.net/10356/89739; http://hdl.handle.net/10220/48362
• Institution: Nanyang Technological University

Amorphous curcumin-chitosan nanoparticle complex (or nanoplex in short) was recently developed as a new solubility enhancement strategy of curcumin (CUR) – a natural herb well known for its vast therapeutic activities. For its subsequent clinical application and commercialization, the present work a...