Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

• Main Authors: Sobti, Meghna, Smits, Callum, Ishmukhametov, Robert, Stock, Daniela, Sandin, Sara, Stewart, Alastair G, Wong, Andrew See Weng
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Cryo-EM; E. Coli ATP Synthase; DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/89777; http://hdl.handle.net/10220/46435

A molecular model that provides a framework for interpreting the wealth of functional information obtained on the E. coli F-ATP synthase has been generated using cryo-electron microscopy. Three different states that relate to rotation of the enzyme were observed, with the central stalk’s ε subunit i...