Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing

Leucine-rich alpha-2-glycoprotein 1 (LRG1) is a novel modulator of TGFβ signaling. This study shows LRG1 expression is increased during wound healing. Lrg1-/- mice show delayed wound healing, altered immune cell infiltration, re-epithelialization, angiogenesis and fibroblast activation in vivo. C...

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Bibliographic Details
Main Author: Liu, Chenghao
Other Authors: Wang Xiaomeng
Format: Theses and Dissertations
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/90069
http://hdl.handle.net/10220/49449
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Institution: Nanyang Technological University
Language: English