Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing
Leucine-rich alpha-2-glycoprotein 1 (LRG1) is a novel modulator of TGFβ signaling. This study shows LRG1 expression is increased during wound healing. Lrg1-/- mice show delayed wound healing, altered immune cell infiltration, re-epithelialization, angiogenesis and fibroblast activation in vivo. C...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2019
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Online Access: | https://hdl.handle.net/10356/90069 http://hdl.handle.net/10220/49449 |
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Institution: | Nanyang Technological University |
Language: | English |