Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH 2

Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH 2

Linear antimicrobial peptides, with their rapid bactericidal mode of action, are well-suited for development as topical antibacterial drugs. We recently designed a synthetic linear 4-residue peptide, BRBR-NH2, with potent bactericidal activity against Staphylococcus aureus (MIC 6.25 μM), the main ca...

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Bibliographic Details
Main Authors: Lau, Qiu Ying, Li, Jianguo, Sani, Marc-Antoine, Sinha, Sheetal, Li, Yan, Ng, Fui Mee, Kang, CongBao, Bhattacharjya, Surajit, Separovic, Frances, Verma, Chandra, Chia, Brian Cheng San
Other Authors: Interdisciplinary Graduate School (IGS)
Format: Article
Language:English
Published: 2019
Subjects:
Antimicrobial Peptide
Membrane Disruptor
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/90094
http://hdl.handle.net/10220/48405
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/90094
http://hdl.handle.net/10220/48405

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