Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis

Compromising the inherent trade-off between transverse resolution and depth of focus (DOF) remains a long-standing issue in optical coherence tomography (OCT). In this work, we report a novel technique—parallel multiple aperture synthesis (pMAS) to simultaneously generate multiple optical apertures...

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Main Authors: Bo, En, Ge, Xin, Yu, Xiaojun, Mo, Jianhua, Liu, Linbo
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2019
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Online Access:https://hdl.handle.net/10356/90098
http://hdl.handle.net/10220/48384
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-900982020-03-07T11:35:32Z Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis Bo, En Ge, Xin Yu, Xiaojun Mo, Jianhua Liu, Linbo School of Chemical and Biomedical Engineering School of Electrical and Electronic Engineering DRNTU::Engineering::Electrical and electronic engineering Aperture Synthesis Optical Coherence Tomography Compromising the inherent trade-off between transverse resolution and depth of focus (DOF) remains a long-standing issue in optical coherence tomography (OCT). In this work, we report a novel technique—parallel multiple aperture synthesis (pMAS) to simultaneously generate multiple optical apertures in an OCT sample arm by employing a two-surface coated mirror. In the proposed pMAS, the DOF is extended by a factor of 16.49 without sacrificing the transverse resolution for proof-of-concept experiments when multiple distinctive apertures are digitally synthesized. The microparticles and tissue experiments demonstrate the feasibility of pMAS to address the fundamental problem of limited DOF in high-resolution OCT. NRF (Natl Research Foundation, S’pore) MOE (Min. of Education, S’pore) NMRC (Natl Medical Research Council, S’pore) Accepted version 2019-05-27T07:53:18Z 2019-12-06T17:40:37Z 2019-05-27T07:53:18Z 2019-12-06T17:40:37Z 2018 Journal Article Bo, E., Ge, X., Yu, X., Mo, J., & Liu, L. (2018). Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis. Applied Optics, 57(13), 3556-3560. doi:10.1364/AO.57.003556 1559-128X https://hdl.handle.net/10356/90098 http://hdl.handle.net/10220/48384 10.1364/AO.57.003556 en Applied Optics © 2018 Optical Society of America. All rights reserved. This paper was published in Applied Optics and is made available with permission of Optical Society of America. 5 p. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Electrical and electronic engineering
Aperture Synthesis
Optical Coherence Tomography
spellingShingle DRNTU::Engineering::Electrical and electronic engineering
Aperture Synthesis
Optical Coherence Tomography
Bo, En
Ge, Xin
Yu, Xiaojun
Mo, Jianhua
Liu, Linbo
Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
description Compromising the inherent trade-off between transverse resolution and depth of focus (DOF) remains a long-standing issue in optical coherence tomography (OCT). In this work, we report a novel technique—parallel multiple aperture synthesis (pMAS) to simultaneously generate multiple optical apertures in an OCT sample arm by employing a two-surface coated mirror. In the proposed pMAS, the DOF is extended by a factor of 16.49 without sacrificing the transverse resolution for proof-of-concept experiments when multiple distinctive apertures are digitally synthesized. The microparticles and tissue experiments demonstrate the feasibility of pMAS to address the fundamental problem of limited DOF in high-resolution OCT.
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Bo, En
Ge, Xin
Yu, Xiaojun
Mo, Jianhua
Liu, Linbo
format Article
author Bo, En
Ge, Xin
Yu, Xiaojun
Mo, Jianhua
Liu, Linbo
author_sort Bo, En
title Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
title_short Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
title_full Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
title_fullStr Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
title_full_unstemmed Extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
title_sort extending axial focus of optical coherence tomography using parallel multiple aperture synthesis
publishDate 2019
url https://hdl.handle.net/10356/90098
http://hdl.handle.net/10220/48384
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