Investigation of surface enhanced Raman spectroscopy for hemozoin detection in malaria diagnosis

We report two methods of surface enhanced Raman spectroscopy (SERS) for hemozoin detection in malaria infected human blood. In the first method, silver nanoparticles were synthesized separately and then mixed with lysed blood; while in the second method, silver nanoparticles were synthesized directl...

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Bibliographic Details
Main Authors: Chen, Keren, Xiong, Aoli, Yuen, Clement, Preiser, Peter, Liu, Quan
Other Authors: Coté, Gerard L.
Format: Conference or Workshop Item
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/90225
http://hdl.handle.net/10220/47230
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Institution: Nanyang Technological University
Language: English
Description
Summary:We report two methods of surface enhanced Raman spectroscopy (SERS) for hemozoin detection in malaria infected human blood. In the first method, silver nanoparticles were synthesized separately and then mixed with lysed blood; while in the second method, silver nanoparticles were synthesized directly inside the parasites of Plasmodium falciparum.