Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells

• المؤلفون الرئيسيون: Diao, Hua Jia, Low, Wei Ching, Milbreta, Ulla, Lu, Q. Richard, Chew, Sing Yian
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Oligodendroglial precursor cells; Remyelination
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/93138; http://hdl.handle.net/10220/40991
• المؤسسة: Nanyang Technological University

Remyelination in the central nervous system (CNS) is critical in the treatment of many neural pathological conditions. Unfortunately, the ability to direct and enhance oligodendrocyte (OL) differentiation and maturation remains limited. It is known that microenvironmental signals, such as substrate...