Encapsulation and controlled release formulations of 5-fluorouracil from natural Lycopodium clavatum spores

• Main Authors: Mundargi, Raghavendra C., Tan, Ee-Lin, Seo, Jeongeun, Cho, Nam-Joon
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Lycopodium clavatum; Spores; Microencapsulation; 5-Fluorouracil; Controlled release
• Online Access: https://hdl.handle.net/10356/93147; http://hdl.handle.net/10220/40599
• Institution: Nanyang Technological University

Cost effective, uniform-size multiparticulate formulations of the chemotherapeutic agent 5-fluorouracil (5-FU) loaded in natural Lycopodium clavatum spores were developed by three different encapsulation techniques: passive, compression and vacuum loading. The surface morphology, and micromeritic pr...