Investigating circular dorsal ruffles through varying substrate stiffness and mathematical modeling

Circular dorsal ruffles (CDRs) are transient actin-rich ring-like structures which form on the dorsal surface of growth-factor stimulated cells. However, the dynamics and mechanism of formation of CDRs are still unknown. It has been observed that CDR formation leads to stress fibers disappearing nea...

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Bibliographic Details
Main Authors: LeDuc, Philip R., Zeng, Yukai, Lai, Tanny, Koh, Cheng Gee, Chiam, Keng-Hwee
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10356/93636
http://hdl.handle.net/10220/7375
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Institution: Nanyang Technological University
Language: English