Optimization of isocratic supercritical fluid chromatography for enantiomer separation

• Main Authors: Chen, Wenda, Reza Haghpanah, Arvind Rajendran, Mohammad Amanullah
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2011
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Organic chromatography
• 在線閱讀: https://hdl.handle.net/10356/93930; http://hdl.handle.net/10220/7187

This paper presents multi-objective optimization analysis and experimental implementation of a single column isocratic supercritical fluid chromatography process for the enantioseparation of flurbiprofen. The single column process is simulated using a detailed model with equilibrium description by a...