Pairwise alignment of the DNA sequence using hypercomplex number representation

• Main Authors: Shu, Jian Jun, Ouw, Li Shan
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biomathematics
• Online Access: https://hdl.handle.net/10356/94026; http://hdl.handle.net/10220/7215
• Institution: Nanyang Technological University

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex number representation of the DNA base-nucleic acid codes and incorporated with the method of dot matrix analysis and various algorithms of sequence alignment. The problem of DNA sequence alignment can be processed in a rather similar way to pairwise alignment of the protein sequence.