Insights into the mechanism of magnetic particle assisted gene delivery

• Main Authors: Ang, Derrick, Nguyen, Q. V., Kayal, S., Preiser, Peter Rainer, Rawat, Rajdeep Singh, Ramanujan, Raju V.
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Materials::Magnetic materials
• Online Access: https://hdl.handle.net/10356/94244; http://hdl.handle.net/10220/7266
• Institution: Nanyang Technological University

In magnetic particle assisted gene delivery DNA is complexed with polymer-coated aggregated magnetic nanoparticles (AMNPs) to effect transfection. In vitro studies based on COS-7 cells were carried out using pEGFP-N1 and pMIR-REPORT-complexed, polyethylenimine (PEI)-coated iron oxide magnetic nanopa...