Binding ability and assembly behavior of β-cyclodextrin complexes with 2,2'-dipyridine and 4,4'-dipyridine

• Main Authors: Liu, Yu, Zhao, Yanli, Zhang, Heng Yi, Yang, En Cui, Guan, Xu Dong
• Format: Article
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/94278; http://hdl.handle.net/10220/6994
• Institution: Nanyang Technological University

Two channel-type supramolecular aggregations 1 and 2 were prepared by the inclusion complex of â-cyclodextrin with 2,2′-dipyridine and 4,4′-dipyridine, respectively, and their binding ability and assembly behavior were investigated comprehensively by X-ray crystallography, 1 H NMR, circular dichroism spectra, and microcalorimetric titration in solution and the solid state. The obtained results revealed that the hydrogen bonds and ð-ð stacking interactions are crucial factors for the formation of the molecular aggregations containing â-cyclodextrin and dipyridines. The disparity of nitrogen atom position in dipyridines leads not only to the distinct crystal system and space group, i.e., monoclinic system (C2) for 1 and triclinic system (P-1) for 2, but also different binding modes and thermodynamical parameters upon complexation of 2,2′-dipyridine and 4,4′-dipyridine with â-cyclodextrin in aqueous solution