Nanofluidic devices and their applications
Recent developments in micro- and nanotechnologies made possible the fabrication of devices integrating a deterministic network of nanochannels, i.e., with at least one dimension in a range from 1 to 100 nm. The proximity of this dimension and the Debye length, the size of biomolecules such as DNA o...
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sg-ntu-dr.10356-944322023-03-04T17:18:28Z Nanofluidic devices and their applications Abgrall, Patrick Nguyen, Nam-Trung School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Recent developments in micro- and nanotechnologies made possible the fabrication of devices integrating a deterministic network of nanochannels, i.e., with at least one dimension in a range from 1 to 100 nm. The proximity of this dimension and the Debye length, the size of biomolecules such as DNA or proteins, or even the slip length, added to the excellent control on the geometry gives unique features to nanofluidic devices. This new class of devices not only finds applications wherever less well-defined porous media, such as electrophoresis gels, have been traditionally used but also give a new insight into the sieving mechanisms of biomolecules and the fluid flow at the nanoscale. Beyond this, the control on the geometry allows smarter design resulting, among others, in new separation principles by taking advantage of the anisotropy. This perspective gives an overview on the fabrication technologies of nanofluidic devices and their applications. In the first part, the current state of the art of nanofluidic fabrication is presented. The second part first discusses the key transport phenomena in nanochannels. Current applications of nanofluidic devices are next discussed. Finally, future challenges and possible applications are highlighted. Accepted version 2012-05-10T03:41:13Z 2019-12-06T18:55:54Z 2012-05-10T03:41:13Z 2019-12-06T18:55:54Z 2008 2008 Journal Article Abgrall, P., & Nguyen, N. T. (2008). Nanofluidic Devices and Their Applications. Analytical Chemistry, 80 (7), 2326-2341. https://hdl.handle.net/10356/94432 http://hdl.handle.net/10220/7836 10.1021/ac702296u 131827 en Analytical chemistry © 2008 American Chemical Society. This is the author created version of a work that has been peer reviewed and accepted for publication by Analytical Chemistry, American Chemical Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: DOI: [http://dx.doi.org/10.1021/ac702296u]. 46 p. application/pdf |
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DRNTU::Engineering::Mechanical engineering Abgrall, Patrick Nguyen, Nam-Trung Nanofluidic devices and their applications |
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Recent developments in micro- and nanotechnologies made possible the fabrication of devices integrating a deterministic network of nanochannels, i.e., with at least one dimension in a range from 1 to 100 nm. The proximity of this dimension and the Debye length, the size of biomolecules such as DNA or proteins, or even the slip length, added to the excellent control on the geometry gives unique features to nanofluidic devices. This new class of devices not only finds applications wherever less well-defined porous media, such as electrophoresis gels, have been traditionally used but also give a new insight into the sieving mechanisms of biomolecules and the fluid flow at the nanoscale. Beyond this, the control on the geometry allows smarter design resulting, among others, in new separation principles by taking advantage of the anisotropy. This perspective gives an overview on the fabrication technologies of nanofluidic devices and their applications. In the first part, the current state of the art of nanofluidic fabrication is presented. The second part first discusses the key transport phenomena in nanochannels. Current applications of nanofluidic devices are next discussed. Finally, future challenges and possible applications are highlighted. |
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School of Mechanical and Aerospace Engineering |
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School of Mechanical and Aerospace Engineering Abgrall, Patrick Nguyen, Nam-Trung |
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Article |
author |
Abgrall, Patrick Nguyen, Nam-Trung |
author_sort |
Abgrall, Patrick |
title |
Nanofluidic devices and their applications |
title_short |
Nanofluidic devices and their applications |
title_full |
Nanofluidic devices and their applications |
title_fullStr |
Nanofluidic devices and their applications |
title_full_unstemmed |
Nanofluidic devices and their applications |
title_sort |
nanofluidic devices and their applications |
publishDate |
2012 |
url |
https://hdl.handle.net/10356/94432 http://hdl.handle.net/10220/7836 |
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1759857228573048832 |