Expression, purification and characterization of C2 domain of milk fat globule-EGF-factor 8-L

• Main Authors: Nanga, Ravi Prakash Reddy, Vivekanandan, Subramanian, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/95128; http://hdl.handle.net/10220/8523
• Institution: Nanyang Technological University

Milk fat globule-EGF-factor 8-L (MFG-E8L) is secreted by activated macrophages and functions as a linker protein or opsonin between the dying cells and phagocytes. MFG-E8L recognizes the apoptotic or dying cells by specifically binding to Phosphatidylserine (PS) exposed on the outer cell surface and...