Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT)

• Main Authors: Misra, Ashish, Pandey, Chhiti, Sze, Siu Kwan, Thanabalu, Thirumaran
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95221; http://hdl.handle.net/10220/9207
• Institution: Nanyang Technological University

Metastasis is a multi-step process which requires the conversion of polarized epithelial cells to mesenchymal cells, Epithelial–Mesenchymal Transition (EMT). EMT is essential during embryonic morphogenesis and has been implicated in the progression of primary tumors towards metastasis. Hypoxia is kn...