Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear....
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sg-ntu-dr.10356-952932020-09-27T20:28:17Z Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging Teo, Ziqiang Tan Nguan Soon School of Biological Sciences Cell migration Keratinocytes Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear. By using immortalized form of keratinocytes (HaCaT) and FIAF-knockdown keratinocytes (HaCaTKD) with and without proliferation inhibitor (Mitomycin C), we aim to determine the effect of FIAF on keratinocyte migration and proliferation during wound healing. [4th Award] 2013-01-31T03:04:13Z 2019-12-06T19:11:59Z 2013-01-31T03:04:13Z 2019-12-06T19:11:59Z 2008 2008 Student Research Poster Teo, Z. (2008, March). Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/95293 http://hdl.handle.net/10220/8992 en © 2008 The Author(s). application/pdf |
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Cell migration Keratinocytes Teo, Ziqiang Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
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Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear. By using immortalized form of keratinocytes (HaCaT) and FIAF-knockdown keratinocytes (HaCaTKD) with and without proliferation inhibitor (Mitomycin C), we aim to determine the effect of FIAF on keratinocyte migration and proliferation during wound healing. [4th Award] |
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Tan Nguan Soon |
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Tan Nguan Soon Teo, Ziqiang |
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Student Research Poster |
author |
Teo, Ziqiang |
author_sort |
Teo, Ziqiang |
title |
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
title_short |
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
title_full |
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
title_fullStr |
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
title_full_unstemmed |
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
title_sort |
understanding the impact of angiopoietin-like protein 4 (angptl4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging |
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2013 |
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https://hdl.handle.net/10356/95293 http://hdl.handle.net/10220/8992 |
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1681057008516595712 |