Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging

Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear....

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Main Author: Teo, Ziqiang
Other Authors: Tan Nguan Soon
Format: Student Research Poster
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/95293
http://hdl.handle.net/10220/8992
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-952932020-09-27T20:28:17Z Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging Teo, Ziqiang Tan Nguan Soon School of Biological Sciences Cell migration Keratinocytes Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear. By using immortalized form of keratinocytes (HaCaT) and FIAF-knockdown keratinocytes (HaCaTKD) with and without proliferation inhibitor (Mitomycin C), we aim to determine the effect of FIAF on keratinocyte migration and proliferation during wound healing. [4th Award] 2013-01-31T03:04:13Z 2019-12-06T19:11:59Z 2013-01-31T03:04:13Z 2019-12-06T19:11:59Z 2008 2008 Student Research Poster Teo, Z. (2008, March). Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/95293 http://hdl.handle.net/10220/8992 en © 2008 The Author(s). application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic Cell migration
Keratinocytes
spellingShingle Cell migration
Keratinocytes
Teo, Ziqiang
Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
description Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear. By using immortalized form of keratinocytes (HaCaT) and FIAF-knockdown keratinocytes (HaCaTKD) with and without proliferation inhibitor (Mitomycin C), we aim to determine the effect of FIAF on keratinocyte migration and proliferation during wound healing. [4th Award]
author2 Tan Nguan Soon
author_facet Tan Nguan Soon
Teo, Ziqiang
format Student Research Poster
author Teo, Ziqiang
author_sort Teo, Ziqiang
title Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
title_short Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
title_full Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
title_fullStr Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
title_full_unstemmed Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
title_sort understanding the impact of angiopoietin-like protein 4 (angptl4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
publishDate 2013
url https://hdl.handle.net/10356/95293
http://hdl.handle.net/10220/8992
_version_ 1681057008516595712