Novel preparation of PLGA/HP55 nanoparticles for oral insulin delivery

• Main Authors: Wu, Zhi Min, Ling, Li, Zhou, Liying, Guo, Xin Dong, Jiang, Wei, Qian, Yu, Luo, Kathy Qian, Zhang, Li Juan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95303; http://hdl.handle.net/10220/9145
• Institution: Nanyang Technological University

The aim of the present study was to develop the PLGA/HP55 nanoparticles with improved hypoglycemic effect for oral insulin delivery. The insulin-loaded PLGA/HP55 nanoparticles were produced by a modified multiple emulsion solvent evaporation method. The physicochemical characteristics, in vitro rele...