Dip-pen nanolithography-based methodology for preparing arrays of nanostructures functionalized with oligonucleotides

Arrays of Au nanostructures have been fabricated based on dip-pen nanolithography and wet chemical etching, whereafter they can be functionalized with alkanethiol-capped oligonucleotides. These retain their hybridization properties on the surfaces of the nanopatterns and can react with complementary...

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Bibliographic Details
Main Authors: Mirkin, Chad A., Zhang, Hua, Li, Zhi
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/95373
http://hdl.handle.net/10220/8606
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Institution: Nanyang Technological University
Language: English
Description
Summary:Arrays of Au nanostructures have been fabricated based on dip-pen nanolithography and wet chemical etching, whereafter they can be functionalized with alkanethiol-capped oligonucleotides. These retain their hybridization properties on the surfaces of the nanopatterns and can react with complementary DNA or particles modified with complementary DNA.