Comparison of principal component analysis and biochemical component analysis in Raman spectroscopy for the discrimination of apoptosis and necrosis in K562 leukemia cells

• Main Authors: Lim, Mayasari, Liu, Quan, Ong, Yi Hong
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Chemical engineering::Biochemical engineering
• Online Access: https://hdl.handle.net/10356/95434; http://hdl.handle.net/10220/9093
• Institution: Nanyang Technological University

Raman spectroscopy has been explored as a promising label-free technique in discriminating apoptosis and necrosis induced cell death in leukemia cells. In addition to Principal component analysis (PCA) as commonly employed in Raman data analysis, another less commonly used but powerful method is Bio...